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Forumsβ€ΊNutrition & Supplementationβ€ΊDigestive enzyme supplementation β€” does it help with GLP-1 GI symptoms? β€Ί Page 2

Digestive enzyme supplementation β€” does it help with GLP-1 GI symptoms?

Dr.GutHealth Wed, May 6, 2026 at 7:23 PM 7 replies 544 viewsPage 2 of 2
DanielChem_CHI
Senior Member
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5,678
Mar 2024
Chicago, IL
May 6, 2026 at 10:13 PM#6

Congrats Dr.GutHealth!! You should be so proud of yourself. πŸŽ‰

Last edited: May 7, 2026 at 12:13 AM
2 16fiona_VT, denise_HTX
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andrew_nyc
Member
534
2,345
Apr 2024
New York, NY
May 6, 2026 at 10:30 PM#7

Clinical perspective on Digestive enzyme supplementation does:

I have managed ~150 patients on GLP-1 therapy and this topic comes up frequently. What the data shows β€” and what I see in practice β€” is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

10 15Dr.NateNeph, PharmD_Rodriguez, julia.endo and 7 others
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quinn_sf
Member
489
2,123
Jun 2024
San Francisco, CA
May 6, 2026 at 10:47 PM#8

Yep. My endo said the same thing about Digestive enzyme.

15 9mona_PHX, andrew_nyc, Dr.EndoEP and 12 others
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pam_stl
Member
267
1,123
Oct 2024
St. Louis, MO
May 6, 2026 at 11:04 PM#9

Reading this thread on Digestive enzyme hits close to home. Night shift nurse β€” I started at 287 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 62 lbs lost β€” my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Digestive enzyme β€” take the leap. It was the best health decision I have ever made. ❀️

48 19SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 45 others
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traveltech_sara
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Jan 2025
Remote, USA
May 6, 2026 at 11:21 PM#10
DanielChem_CHI said:
You should be so proud of yourself

This is exactly right. DanielChem_CHI articulated what I have been trying to explain to my friends for months. The Digestive enzyme aspect is what made the difference for me.

36 16BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 33 others
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