Reading this thread on Incretin effect in hits close to home. Dad of 2 checking in — I started at 273 lbs and felt like I would tried everything.
9 months on tirz and I am a different person. Not just the 48 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about Incretin effect in — take the leap. It was the best health decision I have ever made. ❤️
Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.
Thread quality is excellent — keep it up. 👍
Relevant to Incretin effect in healthy vs — here is my latest bloodwork comparison:
Key improvements: A1C 7.6% → 5.5%, triglycerides 245 → 115 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Congrats patPC_UT!! You should be so proud of yourself. 🎉