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Forumsβ€ΊPharmacology & Mechanismsβ€ΊSemaglutide albumin binding and the C-18 fatty acid linker β€” anyone have experience? β€Ί Page 3

Semaglutide albumin binding and the C-18 fatty acid linker β€” anyone have experience?

cory_ATX Fri, May 1, 2026 at 1:07 AM 27 replies 1,145 viewsPage 3 of 6
jason_sac26
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May 1, 2026 at 5:22 AM#11

sean_dublin β€” wow. I've been looking for this exact info for weeks.

47 13pete_RVA, CarlaRPh_TPA, steph_laguna and 44 others
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Dr.LipidDallas
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Dallas, TX
May 1, 2026 at 5:39 AM#12

Slightly tangential to Semaglutide albumin but cory_ATX reminded me β€” has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered β€” I did search first.

Last edited: May 1, 2026 at 7:39 AM
19 18wei_SG, cory_ATX, lori_vegas and 16 others
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greg_boulder
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Jul 2024
Boulder, CO
May 1, 2026 at 5:56 AM#13

Thanks for sharing this, cory_ATX. A few questions about your Semaglutide albumin experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Semaglutide?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: May 1, 2026 at 7:56 AM
43 10Dr.DermMIA, fiona_VT, denise_HTX and 40 others
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cory_ATX
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Austin, TX
May 1, 2026 at 6:13 AM#14

OP here β€” wow, did not expect this much response! Thank you all for the thoughtful replies on Semaglutide albumin.

To answer Dr.LipidDallas: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion β€” this is exactly why I posted in a science-based community. πŸ™

37 23Dr.PathRoch, mona_PHX, andrew_nyc and 34 others
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BethLabQueen
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May 2024
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May 1, 2026 at 6:30 AM#15

Relevant to Semaglutide albumin binding β€” here is my latest bloodwork comparison:

Key improvements: A1C 7.2% β†’ 5.3%, triglycerides 235 β†’ 105 mg/dL, hsCRP 6.0 β†’ 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: May 1, 2026 at 7:30 AM
11 16wei_SG, cory_ATX, lori_vegas and 8 others
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