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ForumsDosing & ProtocolsPK/PD modeling for tirzepatide — looking for input Page 3

PK/PD modeling for tirzepatide — looking for input

Dr.EndoIndy Tue, Jun 25, 2024 at 7:43 PM 15 replies 1,918 viewsPage 3 of 3
marcus_mpls
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Nov 2024
Minneapolis, MN
Jun 25, 2024 at 11:58 PM#11

+1. This mirrors my journey exactly. The PK/PD modeling for discussion here is so valuable.

Last edited: Jun 26, 2024 at 4:58 AM
16 10bbq_ray_KC, oliver_london, tane_welly and 13 others
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mike_nyc
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New York
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Jun 26, 2024 at 12:15 AM#12

Reading this thread on PK/PD modeling for hits close to home. Night shift nurse — I started at 287 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 62 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about PK/PD modeling for — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Jun 26, 2024 at 4:15 AM
30 23stefan_berlin, Dr.EM_Chicago, pete_RVA and 27 others
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Admin
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Jun 26, 2024 at 12:32 AM#13

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Last edited: Jun 26, 2024 at 4:32 AM
32 23RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 29 others
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FDA_TrackerJim
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Feb 2024
Rockville, MD
Jun 26, 2024 at 12:49 AM#14

Relevant to PK/PD modeling for tirzepatide — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 199 → 99 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

1 14Dr.LeslieOBGYN
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emily_PDX
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Nov 2024
Portland, OR
Jun 26, 2024 at 1:06 AM#15

Congrats marcus_mpls!! Keep going — you're doing incredible. 🎉

27 13PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 24 others
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