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ForumsOral GLP-1 AgonistsOral GLP-1 pipeline overview — all agents in development Page 13

Oral GLP-1 pipeline overview — all agents in development

TrialTracker_MD Mon, Feb 26, 2024 at 4:00 PM 171 replies 52,462 viewsPage 13 of 20
HPLC_Greg
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Research Triangle, NC
Feb 27, 2024 at 10:25 AM#61

Relevant to Oral GLP-1 pipeline overview — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 241 → 111 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Feb 27, 2024 at 4:25 PM
40 1SallyK_inj, CryptoCarl, MariaRD and 37 others
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DoseLogDan
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567
Feb 2025
Montana
Feb 27, 2024 at 10:42 AM#62

Want to share my personal experience related to Oral GLP-1 pipeline overview since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 252 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 52 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Oral GLP-1 pipeline aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

36 19Dr.AddMedPHL, newstart_MO, mia_MS2 and 33 others
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hyun_seoul
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Jul 2024
Seoul, KR
Feb 27, 2024 at 10:59 AM#63

HPLC_Greg — that is really helpful context on Oral GLP-1 pipeline. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

Last edited: Feb 27, 2024 at 2:59 PM
41 7MASHdoc_SA, GenomicsKate, Dr.ObesityMed and 38 others
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tyler_CSCS
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Jun 2024
Phoenix, AZ
Feb 27, 2024 at 11:16 AM#64

Want to share my personal experience related to Oral GLP-1 pipeline overview since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 269 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 59 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Oral GLP-1 pipeline aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Last edited: Feb 27, 2024 at 1:16 PM
46 18amy_econ_NJ, bbq_ray_KC, oliver_london and 43 others
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SleepFixSam
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Nov 2024
Hawaii
Feb 27, 2024 at 11:33 AM#65

HPLC_Greg — that is really helpful context on Oral GLP-1 pipeline. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

3 15fiona_VT, denise_HTX, raj_cambridge
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