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ForumsMetabolic Health & DiabetesGot off metformin for the first time in 8 years - crying happy tears — need advice Page 6

Got off metformin for the first time in 8 years - crying happy tears — need advice

gary_naperville Wed, Sep 10, 2025 at 9:24 PM 29 replies 1,622 viewsPage 6 of 6
anders_CPH
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Sep 11, 2025 at 5:54 AM#26

+1 to LipidDoc_ATL. Especially the point about "This is incredibly helpful..." — I have seen the same in my own experience with Got off metformin for the.

Last edited: Sep 11, 2025 at 9:54 AM
17 22CryptoCarl, MariaRD, AussieAnna and 14 others
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DanielChem_CHI
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Sep 11, 2025 at 6:11 AM#27

Bookmarked 📌 The Got off metformin info in this thread is essential. Coming back to this for sure.

30 4Dr.DermMIA, fiona_VT, denise_HTX and 27 others
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PharmacoVig_BOS
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Sep 11, 2025 at 6:28 AM#28

Clinical perspective on Got off metformin for the first time in:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

Last edited: Sep 11, 2025 at 9:28 AM
46 20DataDave, Dr.GutHealth, amsterdam_pete and 43 others
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CryptoCarl
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May 2024
Arizona
Sep 11, 2025 at 6:45 AM#29

Want to share my personal experience related to Got off metformin for the since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 278 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 38 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Got off metformin aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

8 12BethLabQueen, ChrisMacros, KetoKyle and 5 others
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GenomicsKate
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Oct 2024
Cambridge, MA
Sep 11, 2025 at 7:02 AM#30

Just wanted to say — for anyone reading this Got off metformin thread who is feeling discouraged: it gets better. The first few weeks are the hardest. Hang in there. 💪

Last edited: Sep 11, 2025 at 12:02 PM
4 17claudia_zurich, nancy_portland, rick_sfbay and 1 other
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