Can someone explain how this drug works like I am not a scientist — what worked for you? — Page 2 — Pharmacology & Mechanisms

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Copenhagen, DK

Feb 22, 2025 at 2:44 PM#6

Dr.SurgeonPGH said:
For Can someone explain how this drug, here is what the evidence says:The clinical trial data (SELEC

Gonna push back on this one. Can someone explain how this drug is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

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Dr.PeteFamMed

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Feb 22, 2025 at 3:01 PM#7

Adding my data to this Can someone explain how discussion:

Metric	Baseline	Month 4	Month 8
Weight	270 lbs	240 lbs	205 lbs
A1C	6.4%	6.2%	5.4%
hsCRP	4.0	3.0	1.2

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

Last edited: Feb 22, 2025 at 4:01 PM

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greg_boulder

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Boulder, CO

Feb 22, 2025 at 3:18 PM#8

Dr.KarenChen — wow. I've been looking for this exact info for weeks.

Last edited: Feb 22, 2025 at 5:18 PM

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Dr.GastroMayo

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Mayo Clinic, MN

Feb 22, 2025 at 3:35 PM#9

Slightly tangential to Can someone explain how but ricardo_MIA reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

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