SURPASS-CVOT: tirzepatide cardiovascular outcomes trial design — looking for input

Reading this thread on SURPASS-CVOT tirzepatide hits close to home. Dad of 2 checking in — I started at 277 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 52 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about SURPASS-CVOT — take the leap. It was the best health decision I have ever made. ❤️

Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.

Thread quality is excellent — keep it up. 👍

Relevant to SURPASS-CVOT tirzepatide — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 249 → 119 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Thank you kim_atl_prep! This is incredibly helpful. Taking this to my next appointment. 🙏

+1 to Dr.RenalNash. Especially the point about "SURPASS-CVOT tirzepatide is exactly what..." — I have seen the same in my own experience with SURPASS-CVOT tirzepatide.