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ForumsInsurance & AccessStep therapy requirements — my results so far Page 3

Step therapy requirements — my results so far

LondonLisa Sat, Feb 7, 2026 at 10:36 PM 14 replies 873 viewsPage 3 of 3
MariaRD
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Feb 8, 2026 at 2:51 AM#11

FDA_TrackerJim — wow. This community is amazing.

36 14Dr.NutriCornell, pam_stl, wei_SG and 33 others
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PurityPaulOR
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Feb 8, 2026 at 3:08 AM#12

Slightly tangential to Step therapy requirements but LondonLisa reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Feb 8, 2026 at 6:08 AM
6 21MikeNYC_runner and 3 others
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LeilaHI
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Feb 8, 2026 at 3:25 AM#13

Thanks for sharing this, LondonLisa. A few questions about your Step therapy experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Step therapy?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

6 21mike_nyc, VendorMark, COA_Karl and 3 others
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LondonLisa
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London, UK
Feb 8, 2026 at 3:42 AM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Step therapy requirements.

To answer PurityPaulOR: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Feb 8, 2026 at 5:42 AM
30 2JenPlateau, SallyK_inj, CryptoCarl and 27 others
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Dr.RaviCardio
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Feb 8, 2026 at 3:59 AM#15

Relevant to Step therapy requirements my — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 241 → 111 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

28 22jason_sac26, chris_chi24, tampaLisa73 and 25 others
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