OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with .
To answer pete_manc_UK: yes, I am on compounded sema from a 503B pharmacy.
Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Relevant to Has anyone dealt with — here is my latest bloodwork comparison:
Key improvements: A1C 8.4% → 5.5%, triglycerides 233 → 103 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
ben_calgary said:Thank you all for the thoughtful replies on Has anyone dealt with
This is exactly right. ben_calgary articulated what I have been trying to explain to my friends for months. The Has anyone dealt with aspect is what made the difference for me.
Slightly tangential to Has anyone dealt with but PedsEndoPhilly reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.