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ForumsPharmacology & MechanismsGLP-1R desensitization — looking for input Page 4

GLP-1R desensitization — looking for input

JakeBK_lifts Thu, Mar 7, 2024 at 9:07 AM 16 replies 2,188 viewsPage 4 of 4
denise_HTX
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Jan 2025
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Mar 7, 2024 at 2:47 PM#16

VanRx_Mike — wow. I've been looking for this exact info for weeks.

40 9sarah.morrison, NeuroNate, JessicaH_TX and 37 others
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labquiet_amy
Senior Member
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Mar 2024
Cambridge, MA
Mar 7, 2024 at 3:04 PM#17

Adding my data to this GLP-1R desensitization discussion:

MetricBaselineMonth 5Month 6
Weight240 lbs245 lbs215 lbs
A1C6.4%6.0%5.2%
hsCRP4.04.00.6

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

33 15HPLC_Greg, LibrarianMeg, bri_stats and 30 others
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SteveThurs
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Sep 2024
Wisconsin
Online
Mar 7, 2024 at 3:21 PM#18

Reading this thread on GLP-1R desensitization hits close to home. Night shift nurse — I started at 291 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 66 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about GLP-1R desensitizati — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Mar 7, 2024 at 7:21 PM
50 14SleepFixSam, PurityPaulOR, MaxMetOK and 47 others
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TomFromTexas
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May 2024
Austin, TX
Mar 7, 2024 at 3:38 PM#19

denise_HTX — that is really helpful context on GLP-1R desensitization . Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

32 18PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 29 others
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NurseAsh_DET
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Sep 2024
Detroit, MI
Mar 7, 2024 at 3:55 PM#20

Reading this thread on GLP-1R desensitization hits close to home. Dad of 2 checking in — I started at 273 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 48 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about GLP-1R desensitizati — take the leap. It was the best health decision I have ever made. ❤️

46 12emily_PDX, Dr.SleepRoch, laura_annarbor and 43 others
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