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ForumsOral GLP-1 AgonistsHas anyone dealt with orforglipron food interaction profile? Page 3

Has anyone dealt with orforglipron food interaction profile?

greg_boulder Tue, Nov 11, 2025 at 1:33 PM 25 replies 1,566 viewsPage 3 of 5
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Nov 11, 2025 at 5:48 PM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

31 5PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 28 others
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pete_manc_UK
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Nov 11, 2025 at 6:05 PM#12

Slightly tangential to Has anyone dealt with but SarahChen_PharmD reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

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LeilaHI
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Nov 11, 2025 at 6:22 PM#13
sarah_nash92 said:
Follow-up question: how long did you wait before increasing your dose

This is exactly right. sarah_nash92 articulated what I have been trying to explain to my doctor for months. The Has anyone dealt with aspect is the most important factor.

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LondonLisa
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Nov 11, 2025 at 6:39 PM#14

Saving this for reference. Top-tier content.

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Dr.GutHealth
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Nov 11, 2025 at 6:56 PM#15

Adding my data to this Has anyone dealt with discussion:

MetricBaselineMonth 4Month 8
Weight246 lbs231 lbs211 lbs
A1C7.0%6.2%5.4%
hsCRP5.03.01.2

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

Last edited: Nov 11, 2025 at 11:56 PM
10 1MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 7 others
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