Orforglipron and hepatic first-pass metabolism — anyone have experience?

Slightly tangential to Orforglipron and hepatic but TomTeleRx reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Subscribing to this thread. Orforglipron and hepatic is exactly what I've been researching. 🙏

Slightly tangential to Orforglipron and hepatic but RegAffairsDC reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Agreed. My doctor said the same thing about Orforglipron and.

Slightly tangential to Orforglipron and hepatic but RegAffairsDC reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.