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Tagging this for the weekly digest. 👍
Slightly tangential to SOUL trial preliminary but DataDave reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
JakeSmashed95 said:Follow-up question: how long did you wait before increasing your dose
This is exactly right. JakeSmashed95 articulated what I have been trying to explain to my doctor for months. The SOUL trial preliminary aspect is the most important factor.
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Adding my data to this SOUL trial preliminary discussion:
| Metric | Baseline | Month 4 | Month 8 |
|---|---|---|---|
| Weight | 250 lbs | 245 lbs | 205 lbs |
| A1C | 6.4% | 6.2% | 5.4% |
| hsCRP | 4.0 | 3.0 | 0.8 |
Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.