Tirzepatide half-life and injection timing — PK data

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Tagging this for the weekly digest. 👍

Slightly tangential to Tirzepatide half-life and but julia.endo reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

mia_MS2 said:

Follow-up question: how long did you wait before increasing your dose

This is exactly right. mia_MS2 articulated what I have been trying to explain to my doctor for months. The Tirzepatide half-life and aspect is the most important factor.

Saving this for reference. Top-tier content.

Adding my data to this Tirzepatide half-life and discussion:

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.