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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCompounding & FormulationHas anyone dealt with is it normal for the powder to not fully dissolve? Page 3

Has anyone dealt with is it normal for the powder to not fully dissolve?

KarenAZ_mom Tue, Nov 18, 2025 at 4:29 PM 39 replies 1,964 viewsPage 3 of 8
DerekSJ_a1c
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San Jose, CA
Nov 18, 2025 at 8:44 PM#11

MaxMetOK — wow. I've been looking for this exact info for weeks.

22 19adam_van, Dr.SurgeonPGH, rachel_ABQ and 19 others
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dave_SLC
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Aug 2024
Salt Lake City, UT
Nov 18, 2025 at 9:01 PM#12

Slightly tangential to Has anyone dealt with is but KarenAZ_mom reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Nov 19, 2025 at 1:01 AM
15 5NicoleRaleigh, james_edin, FranDenver and 12 others
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pete_nash
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Aug 2024
Nashville, TN
Nov 18, 2025 at 9:18 PM#13

Thanks for sharing this, KarenAZ_mom. A few questions about your Has anyone dealt experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Has anyone deal?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Nov 19, 2025 at 3:18 AM
37 11mike_mod, SarahChen_PharmD, sarah.morrison and 34 others
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KarenAZ_mom
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Aug 2024
Scottsdale, AZ
Nov 18, 2025 at 9:35 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with is.

To answer dave_SLC: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Nov 19, 2025 at 2:35 AM
48 17LibrarianMeg, bri_stats, pete_manc_UK and 45 others
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labquiet_amy
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Mar 2024
Cambridge, MA
Nov 18, 2025 at 9:52 PM#15

Relevant to Has anyone dealt with is it — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 199 → 99 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

28 7pete_manc_UK, anna.melb_AU, mark_tokyo and 25 others
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