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ForumsCardiovascular OutcomesGLP-1 and atrial fibrillation risk — November 2025 Page 4

GLP-1 and atrial fibrillation risk — November 2025

NurseLeah_Nash Mon, Oct 20, 2025 at 7:42 AM 39 replies 2,030 viewsPage 4 of 8
NurseLeah_Nash
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Oct 20, 2025 at 1:22 PM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on GLP-1 and atrial.

To answer KetoKyle: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

33 10RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 30 others
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BethLabQueen
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Oct 20, 2025 at 1:39 PM#17

Relevant to GLP-1 and atrial fibrillation — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 241 → 111 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

11 11Dr.PulmRoch, maya_sedona, stefan_berlin and 8 others
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sarah.morrison
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Oct 20, 2025 at 1:56 PM#18

100%. My provider said the same thing about GLP-1 and atrial.

49 17tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 46 others
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Dr.ReproEndo
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Jan 2024
Scottsdale, AZ
Oct 20, 2025 at 2:13 PM#19

Slightly tangential to GLP-1 and atrial but Dr.Martinez reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

32 5GraceAZ_72, carl_compliance, DanielChem_CHI and 29 others
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BiostatsBrad
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Durham, NC
Oct 20, 2025 at 2:30 PM#20
NurseLeah_Nash said:
Thank you all for the thoughtful replies on GLP-1 and atrial

This is exactly right. NurseLeah_Nash articulated what I have been trying to explain to my doctor for months. The GLP-1 and atrial aspect is the most important factor.

24 15NicoleRaleigh, james_edin, FranDenver and 21 others
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