🍪 The GLP Lounge uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesHeart failure hospitalization reduction on semaglutide — looking for input Page 3

Heart failure hospitalization reduction on semaglutide — looking for input

marcus_mpls Wed, Sep 10, 2025 at 6:31 PM 28 replies 1,408 viewsPage 3 of 6
Admin
Administrator
2,456
9,812
Oct 2023
Online
Sep 10, 2025 at 10:46 PM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Last edited: Sep 11, 2025 at 2:46 AM
43 0PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 40 others
Reply Quote Save Share Report
Dr.SurgeonPGH
Senior Member
1,345
6,789
Mar 2024
Pittsburgh, PA
Sep 10, 2025 at 11:03 PM#12

Slightly tangential to Heart failure but Dr.GastroMayo reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

35 18TomTeleRx, DoseLogDan, SleepFixSam and 32 others
Reply Quote Save Share Report
cory_ATX
Member
456
2,123
Jul 2024
Austin, TX
Sep 10, 2025 at 11:20 PM#13
mel_PDX said:
Follow-up question: how long did you wait before increasing your dose

This is exactly right. mel_PDX articulated what I have been trying to explain to my doctor for months. The Heart failure aspect is the most important factor.

32 13mona_PHX, andrew_nyc, Dr.EndoEP and 29 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides

GL Biochem (Shanghai) Ltd. — Direct Manufacturer

Est. 1998. The synthesis house behind the vials you send for testing. ISO 9001 and cGMP certified, 1,500+ staff, batch-specific COA with every order.

Browse GL Biochem
Dr.DermMIA
Member
456
2,123
May 2024
Miami, FL
Sep 10, 2025 at 11:37 PM#14

Saving this for reference. Top-tier content.

44 11PeptideChemSF, A1cHero_PHX, Dr.RenalNash and 41 others
Reply Quote Save Share Report
dan_philly
Member
456
2,123
Jul 2024
Philadelphia, PA
Sep 10, 2025 at 11:54 PM#15

Adding my data to this Heart failure discussion:

MetricBaselineMonth 5Month 8
Weight278 lbs218 lbs203 lbs
A1C7.2%6.0%5.4%
hsCRP7.04.01.2

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.

Last edited: Sep 11, 2025 at 2:54 AM
12 16EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 9 others
Reply Quote Save Share Report

Similar Threads

SELECT trial: 20% MACE reduction — mechanistic deep dive7 replies
Semaglutide cardiovascular benefit independent of weight loss11 replies
STEP-HFpEF: semaglutide in heart failure with preserved EF15 replies
GLP-1 and arterial inflammation — hsCRP and IL-6 reduction data18 replies
Lp(a) on GLP-1 agonists — any impact on this risk factor?8 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register