Jun 14, 2025 at 1:40 PM#11
nick_newbie — wow. This community is amazing.
Last edited: Jun 14, 2025 at 2:40 PM
7 0RunnerRach, TrialNerd_Beth, HPLC_Greg and 4 others
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Jun 14, 2025 at 1:57 PM#12
Slightly tangential to Tirzepatide dual agonism but MASHdoc_SA reminded me — what is the latest on the oral formulations?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
29 14alex_tucson, kevin_tulsa, Dr.PainCLE and 26 others
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Jun 14, 2025 at 2:14 PM#13
Thanks for sharing this, MASHdoc_SA. A few questions about your Tirzepatide dual experience:
- What dose did you start at?
- How long before you noticed side effects improving?
- Did your provider have any specific recommendations about Tirzepatide?
I am in a similar boat and trying to learn from others' experiences before my next appointment.
Last edited: Jun 14, 2025 at 8:14 PM
5 12mona_PHX, andrew_nyc, Dr.EndoEP and 2 others
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Jun 14, 2025 at 2:31 PM#14
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Tirzepatide dual agonism.
To answer pam_columbus: yes, I am on compounded sema from a 503B pharmacy.
Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Last edited: Jun 14, 2025 at 5:31 PM
44 4LabKate, kate.chem, DataDave and 41 others
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Jun 14, 2025 at 2:48 PM#15
Relevant to Tirzepatide dual agonism GIP + — here is my latest bloodwork comparison:
Key improvements: A1C 8.4% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
39 24ChrisMacros, KetoKyle, CanadaChris and 36 others
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