Retatrutide kidney outcomes — anyone have experience?

Saving this for reference. Top-tier content.

Want to share my personal experience related to Retatrutide kidney outcomes since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 256 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 51 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Retatrutide kidney aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Relevant to Retatrutide kidney outcomes — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 247 → 117 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Want to share my personal experience related to Retatrutide kidney outcomes since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 273 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 58 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Retatrutide kidney aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

josh_phd_bmore — that is really helpful context on Retatrutide kidney. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.