Jun 6, 2026 at 2:30 AM#6
Subscribing to this thread. Powerlifting on GLP-1 is exactly what I've been researching. 🙏
19 10TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 16 others
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Jun 6, 2026 at 2:47 AM#7
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Powerlifting on GLP-1 .
To answer KevinCompounds: I started tracking everything in a spreadsheet from day 1.
Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
47 12JennaRN, LabKate, kate.chem and 44 others
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Jun 6, 2026 at 3:04 AM#8
Adding my data to this Powerlifting on GLP-1 discussion:
| Metric | Baseline | Month 4 | Month 8 |
|---|---|---|---|
| Weight | 270 lbs | 235 lbs | 205 lbs |
| A1C | 6.4% | 6.2% | 5.4% |
| hsCRP | 4.0 | 3.0 | 1.2 |
Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.
15 19AussieAnna, BethLabQueen, ChrisMacros and 12 others
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Jun 6, 2026 at 3:21 AM#9
+1 to JakeBK_lifts. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with Powerlifting on GLP-1 .
Last edited: Jun 6, 2026 at 4:21 AM
3 21jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner
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Jun 6, 2026 at 3:38 AM#10
Slightly tangential to Powerlifting on GLP-1 but sarah_nash92 reminded me — has anyone else noticed changes in their alcohol tolerance?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Last edited: Jun 6, 2026 at 5:38 AM
12 14JenMemphis, pat_auckland, Dr.GastroMayo and 9 others
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