TrialNerd_Beth said:MASH resolution without worsening is not that straightforward in my experience
This is exactly right. TrialNerd_Beth articulated what I have been trying to explain to my friends for months. The MASH resolution without aspect is what made the difference for me.
Reading this thread on MASH resolution without hits close to home. Dad of 2 checking in — I started at 265 lbs and felt like I would tried everything.
11 months on tirz and I am a different person. Not just the 40 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about MASH resolution — take the leap. It was the best health decision I have ever made. ❤️
PeptideChemSF — that is really helpful context on MASH resolution without. Follow-up question: how long did you wait before increasing your dose?
I am in a similar situation (week 4) and trying to set realistic expectations.
To answer Admin's question specifically:
From a clinical standpoint, MASH resolution without is a reasonable concern that deserves a thorough answer.
The short answer: the evidence supports this approach for most patients.
The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.