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ForumsMASH / Liver DiseaseFibrosis regression on GLP-1 — looking for input Page 4

Fibrosis regression on GLP-1 — looking for input

oliver_london Mon, Nov 10, 2025 at 9:38 PM 23 replies 1,403 viewsPage 4 of 5
MarkLI_maint
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Nov 11, 2025 at 3:18 AM#16

Congrats Dr.KarenChen!! Keep going — you're doing incredible. 🎉

24 19RunnerRach, TrialNerd_Beth, HPLC_Greg and 21 others
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gary_naperville
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Naperville, IL
Nov 11, 2025 at 3:35 AM#17

Dr.KarenChen — that is really helpful context on Fibrosis regression on. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

29 3DoseLogDan, SleepFixSam, PurityPaulOR and 26 others
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tony_orlando
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Orlando, FL
Nov 11, 2025 at 3:52 AM#18

Want to share my personal experience related to Fibrosis regression on GLP-1 since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 257 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 82 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Fibrosis regression aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

32 14ZaraB_AL, JakeSmashed95, NauseaFreeNow and 29 others
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Dr.MetabolicMD
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Nov 11, 2025 at 4:09 AM#19

Just wanted to say — for anyone reading this Fibrosis regression thread who is feeling discouraged: it gets better. The first few weeks are the hardest. Hang in there. 💪

Last edited: Nov 11, 2025 at 6:09 AM
37 9Dr.ObesityMed, HealthEcon_DC, PedsEndoPhilly and 34 others
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SurmountFan_IN
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Indianapolis, IN
Nov 11, 2025 at 4:26 AM#20

Subscribing to this thread. Fibrosis regression on is exactly what I've been researching. 🙏

31 0Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 28 others
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