Jun 8, 2026 at 9:26 AM#12
Slightly tangential to Endotoxin testing methods but DebRD_ATL reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
29 1paul_denver, TinaHashiRN, robert_kc and 26 others
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Jun 8, 2026 at 9:43 AM#13
cory_ATX said:Follow-up question: how long did you wait before increasing your dose
This is exactly right. cory_ATX articulated what I have been trying to explain to my doctor for months. The Endotoxin testing methods aspect is the most important factor.
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Jun 8, 2026 at 10:00 AM#14
Saving this for reference. Top-tier content.
4 19Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 1 other
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Jun 8, 2026 at 10:17 AM#15
Adding my data to this Endotoxin testing methods discussion:
| Metric | Baseline | Month 4 | Month 8 |
|---|---|---|---|
| Weight | 274 lbs | 244 lbs | 199 lbs |
| A1C | 6.8% | 6.2% | 5.4% |
| hsCRP | 8.0 | 3.0 | 0.8 |
Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.
45 4julia.endo, JessicaM_2024, TomFromTexas and 42 others
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