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ForumsMASH / Liver DiseaseHas anyone dealt with what even is mash? my doc mentioned it and i panicked? Page 2

Has anyone dealt with what even is mash? my doc mentioned it and i panicked?

JessicaH_TX Thu, Sep 18, 2025 at 6:36 AM 21 replies 1,461 viewsPage 2 of 5
PharmacoVig_BOS
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Sep 18, 2025 at 9:26 AM#6
HPLC_Greg said:
my doc mentioned it and i panicked

I respect HPLC_Greg perspective but I think this oversimplifies things a bit. Re: Has anyone dealt with what — the effect size varies considerably by population.

I am not saying HPLC_Greg wrong entirely — just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.

31 13amsterdam_pete, LondonLisa, mike_nyc and 28 others
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Dr.RaviCardio
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Sep 18, 2025 at 9:43 AM#7

Relevant to Has anyone dealt with what — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 243 → 113 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Sep 18, 2025 at 10:43 AM
14 20anna.melb_AU, mark_tokyo, hans_munich and 11 others
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GenomicsKate
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Sep 18, 2025 at 10:00 AM#8

Thank you Dr.KarenChen! This is incredibly helpful. Bookmarking for later. 🙏

44 22MarkLI_maint, Dr.PeteFamMed, claudia_zurich and 41 others
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FranDenver
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Sep 18, 2025 at 10:17 AM#9

Slightly tangential to Has anyone dealt with but A1cHero_PHX reminded me — has the insurance landscape changed recently?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Sep 18, 2025 at 4:17 PM
12 5MASHdoc_SA, GenomicsKate, Dr.ObesityMed and 9 others
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Admin
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Sep 18, 2025 at 10:34 AM#10

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

35 6PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 32 others
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