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ForumsSemaglutide (Ozempic / Wegovy)Semaglutide cardiovascular benefit: SELECT trial deep dive — looking for input Page 6

Semaglutide cardiovascular benefit: SELECT trial deep dive — looking for input

MaxMetOK Tue, Dec 17, 2024 at 2:04 PM 56 replies 2,950 viewsPage 6 of 12
COA_Karl
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Dec 17, 2024 at 10:34 PM#26

This thread is incredible for Semaglutide info. Better than most online groups.

25 12matt_MKE, Dr.ReproEndo, lucas_SP_BR and 22 others
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DataDave
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Dec 17, 2024 at 10:51 PM#27
emily_PDX said:
I started my GLP-1 journey in October 2024 at 274 lbs with prediabetes and hypertension

Gonna push back on this one. Semaglutide cardiovascular benefit is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

40 7mike_nyc, VendorMark, COA_Karl and 37 others
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pete_manc_UK
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Mar 2024
Manchester, UK
Dec 17, 2024 at 11:08 PM#28

Want to share my personal experience related to Semaglutide cardiovascular since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 280 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 75 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Semaglutide aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Dec 18, 2024 at 5:08 AM
3 9FitDadDave, RunnerRach, TrialNerd_Beth
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Dr.SleepRoch
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Dec 17, 2024 at 11:25 PM#29

Saving this for reference. Quality thread.

Last edited: Dec 18, 2024 at 3:25 AM
31 4tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 28 others
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BrianDallas92
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Oct 2024
Dallas, TX
Dec 17, 2024 at 11:42 PM#30

COA_Karl — that is really helpful context on Semaglutide. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

Last edited: Dec 18, 2024 at 12:42 AM
27 15GraceAZ_72, carl_compliance, DanielChem_CHI and 24 others
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