Slightly tangential to 72-year-old but Admin reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Yep. My endo said the same thing about 72-year-old.
Reading this thread on 72-year-old hits close to home. Night shift nurse — I started at 283 lbs and felt like I would tried everything.
9 months on tirz and I am a different person. Not just the 58 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about 72-year-old — take the leap. It was the best health decision I have ever made. ❤️
As a pharmacist, I want to add some clinical context to this discussion on 72-year-old transformation proving age.
Building on what newstart_MO said — the evidence base here is robust. The key publications to reference are from the FLOW program[1].
Key clinical points:
- Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
- Side effect profile is predictable and usually manageable with standard protocols
- Monitoring should include baseline labs and follow-up at 3-month intervals
- Patient education significantly improves outcomes and adherence
Standard disclaimer: this is educational, not individualized medical advice.
[1] See thread title for relevant study identification.