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Forumsβ€ΊProgress & Lab Resultsβ€ΊONE HUNDRED POUNDS DOWN LETS GOOO β€Ί Page 3

ONE HUNDRED POUNDS DOWN LETS GOOO

JakeSmashed95 Sun, Mar 15, 2026 at 6:13 AM 27 replies 1,129 viewsPage 3 of 6
Admin
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Mar 15, 2026 at 10:28 AM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. πŸ‘

Last edited: Mar 15, 2026 at 2:28 PM
15 3PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 12 others
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newstart_MO
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Mar 15, 2026 at 10:45 AM#12

Clinical perspective on ONE HUNDRED POUNDS DOWN LETS GOOO:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows β€” and what I see in practice β€” is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

20 8LibrarianMeg, bri_stats, pete_manc_UK and 17 others
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NeuroNate
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Mar 15, 2026 at 11:02 AM#13
Admin said:
Consult your healthcare provider

I respect Admin perspective but I think this oversimplifies things a bit. Re: ONE HUNDRED POUNDS DOWN LETS β€” the subgroup analyses show meaningful heterogeneity.

I am not saying Admin wrong entirely β€” just that the picture is more nuanced than a blanket statement. The STEP data specifically shows dose-dependent variation.

36 0sarah_TO, wendy_avl, jason_paloalto and 33 others
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Dr.RaviCardio
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Mar 15, 2026 at 11:19 AM#14

Reading this thread on ONE HUNDRED POUNDS DOWN hits close to home. Night shift nurse β€” I started at 291 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 66 lbs lost β€” my energy, my mood, my relationship with food. All transformed.

If you are on the fence about ONE HUNDRED POUNDS β€” take the leap. It was the best health decision I have ever made. ❀️

31 13hans_munich, jason_sac26, chris_chi24 and 28 others
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jim_asheville
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Mar 15, 2026 at 11:36 AM#15

Bookmarked πŸ“Œ The ONE HUNDRED POUNDS info in this thread is essential. Coming back to this for sure.

Last edited: Mar 15, 2026 at 2:36 PM
34 7LarryQC_SD, wanda_boise, NurseAsh_DET and 31 others
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