Feb 18, 2026 at 6:13 PM#6
Subscribing to this thread. The scale has not moved is exactly what I've been researching. 🙏
Last edited: Feb 18, 2026 at 10:13 PM
49 20ingrid_STO, pete_nash, hank_denver and 46 others
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Feb 18, 2026 at 6:30 PM#7
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on The scale has not moved.
To answer Dr.BariatricHTX: yes, I am on compounded sema from a 503B pharmacy.
Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Last edited: Feb 19, 2026 at 12:30 AM
43 3TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 40 others
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Feb 18, 2026 at 6:47 PM#8
Relevant to The scale has not moved in 3 — here is my latest bloodwork comparison:
Key improvements: A1C 8.4% → 5.5%, triglycerides 245 → 115 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Last edited: Feb 18, 2026 at 7:47 PM
8 7mark_tokyo, hans_munich, jason_sac26 and 5 others
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Feb 18, 2026 at 7:04 PM#9
JenPlateau said:Thank you all for the thoughtful replies on The scale has not moved
This is exactly right. JenPlateau articulated what I have been trying to explain to my friends for months. The The scale has not moved aspect is what made the difference for me.
Last edited: Feb 18, 2026 at 10:04 PM
5 19carl_compliance, DanielChem_CHI, marco_milano and 2 others
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Feb 18, 2026 at 7:21 PM#10
Slightly tangential to The scale has not moved but LibrarianMeg reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
47 23PurityPaulOR, MaxMetOK, MounjBrad and 44 others
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