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ForumsSide Effects & ManagementKidney stone risk on GLP-1 — 6 month update Page 3

Kidney stone risk on GLP-1 — 6 month update

steve_okc Tue, Dec 9, 2025 at 5:29 AM 12 replies 1,200 viewsPage 3 of 3
AussieAnna
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Dec 9, 2025 at 9:44 AM#11
LipidDoc_ATL said:
Kidney stone risk on GLP-1 6 month is not that straightforward in my experience

This is exactly right. LipidDoc_ATL articulated what I have been trying to explain to my doctor for months. The Kidney stone risk on aspect is the most important factor.

Last edited: Dec 9, 2025 at 10:44 AM
50 16TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 47 others
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Dr.ObesityMed
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Dec 9, 2025 at 10:01 AM#12

Reading this thread on Kidney stone risk on hits close to home. Night shift nurse — I started at 279 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 54 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Kidney stone risk on — take the leap. It was the best health decision I have ever made. ❤️

25 23PharmacoVig_BOS, SurmountFan_IN, PeptideChemSF and 22 others
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andrew_nyc
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Dec 9, 2025 at 10:18 AM#13

Dr.BariatricHTX — that is really helpful context on Kidney stone risk on. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

Last edited: Dec 9, 2025 at 3:18 PM
33 22PharmD_Rodriguez, julia.endo, JessicaM_2024 and 30 others
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pat_auckland
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Dec 9, 2025 at 10:35 AM#14

To answer Dr.ObesityMed's question specifically:

From a clinical standpoint, Kidney stone risk on GLP-1 6 is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

49 19MeganSA_TX, LarryQC_SD, wanda_boise and 46 others
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Dr.NutriCornell
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Dec 9, 2025 at 10:52 AM#15

Bookmarked 📌 The Kidney stone risk on info in this thread is essential. Coming back to this for sure.

Last edited: Dec 9, 2025 at 12:52 PM
41 8pat_auckland, Dr.GastroMayo, JakeBK_lifts and 38 others
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