Nov 18, 2025 at 8:09 PM#26
Same experience here with GLP-1 and menstrual. MaxMetOK described it perfectly.
Last edited: Nov 19, 2025 at 1:09 AM
5 18bbq_ray_KC, oliver_london, tane_welly and 2 others
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Nov 18, 2025 at 8:26 PM#27
TrialNerd_Beth said:I started my GLP-1 journey in October 2024 at 256 lbs with prediabetes and hypertension
Gonna push back on this one. GLP-1 and menstrual irregularity is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.
Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.
49 0PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 46 others
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Nov 18, 2025 at 8:43 PM#28
Want to share my personal experience related to GLP-1 and menstrual since I think it might help others in a similar situation.
I started my GLP-1 journey in March 2025 at 262 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.
Now, 18 months later: I am down 37 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The GLP-1 and menstrual aspect specifically was something that made a big difference in my journey.
This forum was my go-to resource throughout.
25 19emma_london, tammy_FL, Dr.LipidDallas and 22 others
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Nov 18, 2025 at 9:17 PM#30
marcus_mpls — that is really helpful context on GLP-1 and menstrual. Follow-up question: how long did you wait before increasing your dose?
I am in a similar situation (week 4) and trying to set realistic expectations.
1 14RickReta_CO
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