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ForumsExercise & Body CompositionCreatine kinase elevations on GLP-1 — looking for input Page 3

Creatine kinase elevations on GLP-1 — looking for input

BethLabQueen Tue, Dec 17, 2024 at 9:08 AM 51 replies 2,621 viewsPage 3 of 11
Admin
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Dec 17, 2024 at 1:23 PM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Last edited: Dec 17, 2024 at 5:23 PM
21 13PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 18 others
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NurseLeah_Nash
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Dec 17, 2024 at 1:40 PM#12

Clinical perspective on Creatine kinase elevations on GLP-1 :

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

37 0BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 34 others
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Dr.SportsMedIN
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Dec 17, 2024 at 1:57 PM#13
Admin said:
Consult your healthcare provider

I respect Admin perspective but I think this oversimplifies things a bit. Re: Creatine kinase elevations on — the subgroup analyses show meaningful heterogeneity.

I am not saying Admin wrong entirely — just that the picture is more nuanced than a blanket statement. The STEP data specifically shows dose-dependent variation.

32 8adam_van, Dr.SurgeonPGH, rachel_ABQ and 29 others
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Dr.GutHealth
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Dec 17, 2024 at 2:14 PM#14

Reading this thread on Creatine kinase hits close to home. Night shift nurse — I started at 263 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 38 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Creatine kinase — take the leap. It was the best health decision I have ever made. ❤️

29 18Dr.RaviCardio, jennifer_SEA, tyler_CSCS and 26 others
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nick_newbie
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Dec 17, 2024 at 2:31 PM#15

Bookmarked 📌 The Creatine kinase info in this thread is essential. Coming back to this for sure.

Last edited: Dec 17, 2024 at 5:31 PM
28 10wanda_boise, NurseAsh_DET, BenResearch_OR and 25 others
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