🍪 The GLP Lounge uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseSemaglutide and MASH — March 2026 Page 9

Semaglutide and MASH — March 2026

sophie_paris Tue, Dec 17, 2024 at 7:15 PM 42 replies 2,138 viewsPage 9 of 9
amy_econ_NJ
Member
567
2,567
May 2024
Princeton, NJ
Dec 18, 2024 at 8:00 AM#41

Saving this for reference. Quality thread.

1 20Dr.SportsMedIN
Reply Quote Save Share Report
Dr.EndoIndy
Member
267
1,234
Oct 2024
Indianapolis, IN
Dec 18, 2024 at 8:17 AM#42

Slightly tangential to Semaglutide and MASH but AmyNC_wife reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

48 8LeilaHI, marcus_mpls, DeniseRN_TPA and 45 others
Reply Quote Save Share Report
jason_paloalto
Member
212
890
Nov 2024
Palo Alto, CA
Dec 18, 2024 at 8:34 AM#43

Relevant to Semaglutide and MASH March — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 249 → 119 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

6 5mona_PHX, andrew_nyc, Dr.EndoEP and 3 others
Reply Quote Save Share Report
Dr.CardioMD
VIP Member
2,678
14,567
Dec 2023
Cleveland, OH
Dec 18, 2024 at 8:51 AM#44

Want to share my personal experience related to Semaglutide and MASH March since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 245 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 55 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Semaglutide and MASH aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Dec 18, 2024 at 2:51 PM
21 13roxy_nash, tony_orlando, Dr.NephBHM_UK and 18 others
Reply Quote Save Share Report
DerekSJ_a1c
Member
378
1,678
Aug 2024
San Jose, CA
Dec 18, 2024 at 9:08 AM#45

jason_paloalto — that is really helpful context on Semaglutide and MASH . Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

33 17AttorneyGrant, DebRD_ATL, KristenIndy and 30 others
Reply Quote Save Share Report
1789

Similar Threads

Survodutide MASH Phase 2b — histological improvement data9 replies
Semaglutide and MASH — liver fat reduction quantification13 replies
Non-invasive MASH biomarkers — FibroScan, ELF, FIB-4 on GLP-110 replies
ALT normalization rates on GLP-1 — pooled trial data20 replies
GLP-1 hepatoprotection — direct vs indirect mechanisms16 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register