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ForumsSide Effects & ManagementDay 3 on sema and I feel like death warmed over — need advice Page 3

Day 3 on sema and I feel like death warmed over — need advice

roxy_nash Sat, Aug 16, 2025 at 7:33 AM 50 replies 2,150 viewsPage 3 of 10
hans_munich
Member
534
2,345
Jul 2024
Munich, DE
Aug 16, 2025 at 11:48 AM#11

Thank you lucas_SP_BR! This is incredibly helpful. Bookmarking for later. 🙏

37 20kevin_tulsa, Dr.PainCLE, mike_mealprep and 34 others
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bri_stats
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789
3,456
May 2024
Seattle, WA
Aug 16, 2025 at 12:05 PM#12

Slightly tangential to Day 3 on sema and I feel but roxy_nash reminded me — has the insurance landscape changed recently?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

11 13mike.trainer_LA, sarah_nash92, FitDadDave and 8 others
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greg_boulder
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345
1,567
Jul 2024
Boulder, CO
Aug 16, 2025 at 12:22 PM#13

Thanks for sharing this, roxy_nash. A few questions about your Day 3 on sema and I experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Day 3 on sema?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Aug 16, 2025 at 2:22 PM
42 22Dr.DermMIA, fiona_VT, denise_HTX and 39 others
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roxy_nash
Member
178
890
Dec 2024
Nashville, TN
Aug 16, 2025 at 12:39 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Day 3 on sema and I feel.

To answer bri_stats: my doctor and I discussed the options and went with brand.

Quick update: I have noticed more improvement since posting this. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

14 6Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 11 others
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dan_philly
Member
456
2,123
Jul 2024
Philadelphia, PA
Aug 16, 2025 at 12:56 PM#15

Adding my data to this Day 3 on sema and I feel discussion:

MetricBaselineMonth 3Month 6
Weight268 lbs233 lbs213 lbs
A1C7.2%5.8%5.2%
hsCRP7.02.01.0

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.

18 6EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 15 others
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