Skin rash at injection site — anyone have experience?

Yes, definitely rotate! Injecting in the same location repeatedly almost guarantees lipohypertrophy or nodule formation. Beyond the cosmetic issue, injecting into lipohypertrophic tissue can cause erratic medication absorption — meaning you might get unpredictable drug levels, which could explain inconsistent side effects or efficacy.

Think of your abdomen as a clock face around your navel (avoiding 2 inches around the navel itself). Move clockwise each week. Then switch to thighs or upper arms for a month. Give each site at least 4-6 weeks before reusing.

Thank you all! I'm definitely guilty of injecting in a too-small area. Going to start using a rotation chart and switch to thighs for a while to let my abdomen recover. Really helpful practical advice here — my prescribing doc literally said "inject in your stomach" and nothing more.

One more tip that nobody told me — ice the area for 30 seconds before injecting. Numbs the skin so it hurts less AND I think the vasoconstriction helps reduce local reactions. My lumps completely stopped forming once I started doing this plus proper rotation.