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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingHas anyone dealt with moisture content analysis for lyophilized peptides? Page 7

Has anyone dealt with moisture content analysis for lyophilized peptides?

newstart_MO Thu, May 30, 2024 at 8:42 AM 54 replies 2,788 viewsPage 7 of 11
PharmD_Rodriguez
Senior Member
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Jan 2024
Miami, FL
May 30, 2024 at 6:37 PM#31

To answer EndoResFellow's question specifically:

From a clinical standpoint, Has anyone dealt with moisture is something I discuss with patients regularly.

The short answer: discuss this specific situation with your prescribing provider.

The longer answer involves weighing the risk-benefit ratio for your individual situation, which I am happy to elaborate on if helpful.

8 24paul_denver, TinaHashiRN, robert_kc and 5 others
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AttorneyGrant
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Apr 2024
Washington, DC
May 30, 2024 at 6:54 PM#32

+1 to AmyNC_wife. Especially the point about "I've been looking for this exact info fo..." — I have seen the same in my own experience with Has anyone dealt with.

26 13laura_annarbor, JenMemphis, pat_auckland and 23 others
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newstart_MO
New Member
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Feb 2026
Springfield, MO
May 30, 2024 at 7:11 PM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with.

To answer newstart_MO: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

10 18HPLC_Greg, LibrarianMeg, bri_stats and 7 others
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Dr.EndoIndy
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Oct 2024
Indianapolis, IN
May 30, 2024 at 7:28 PM#34

+1 to VendorMark. Especially the point about "Dad of 2 checking in — I started at 277 ..." — I have seen the same in my own experience with Has anyone dealt with.

26 12DeniseRN_TPA, SandraNC_45, Dr.EndoIndy and 23 others
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MikeFit_NJ
Senior Member
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Apr 2024
New Jersey
May 30, 2024 at 7:45 PM#35

Can confirm — my data shows the same pattern.

8 7Dr.EndoIndy, tom_AK, josh_phd_bmore and 5 others
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