OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on GLP-1 and gluconeogenesis.
To answer DerekSJ_a1c: I get my labs done through Quest every 3 months.
Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Relevant to GLP-1 and gluconeogenesis — here is my latest bloodwork comparison:
Key improvements: A1C 7.2% → 5.3%, triglycerides 235 → 105 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Yep. My endo said the same thing about GLP-1 and gluconeoge.
Slightly tangential to GLP-1 and gluconeogenesis but tampaLisa73 reminded me — has the insurance landscape changed recently?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
matt_MKE said:Thank you all for the thoughtful replies on GLP-1 and gluconeogenesis
This is exactly right. matt_MKE articulated what I have been trying to explain to my friends for months. The GLP-1 and gluconeogenesis aspect is what made the difference for me.