Sep 19, 2025 at 4:11 AM#16
Congrats mia_MS2!! Keep going — you're doing incredible. 🎉
44 9CryptoCarl, MariaRD, AussieAnna and 41 others
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Sep 19, 2025 at 4:28 AM#17
jason_paloalto's experience with Small molecule vs peptide resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.
The main difference: I had more GI issues initially. But the overall trajectory has been remarkably similar. Down 57 lbs in 12 months.
One thing I would add that jason_paloalto did not mention: insurance coverage was a major hurdle.
Last edited: Sep 19, 2025 at 6:28 AM
20 4Dr.DermMIA, fiona_VT, denise_HTX and 17 others
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Sep 19, 2025 at 4:45 AM#18
Bookmarked 📌 The Small molecule vs info in this thread is essential. Coming back to this for sure.
12 8james_edin, FranDenver, Dr.BariatricHTX and 9 others
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Sep 19, 2025 at 5:02 AM#19
Clinical perspective on Small molecule vs peptide GLP-1 agonists:
I have managed over 200 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.
For this specific question, I would recommend: getting comprehensive baseline labs first.
42 12TinaHashiRN, robert_kc, dan_philly and 39 others
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Sep 19, 2025 at 5:19 AM#20
Subscribing to this thread. Small molecule vs peptide is exactly what I've been researching. 🙏
30 22claudia_zurich, nancy_portland, rick_sfbay and 27 others
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