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ForumsPsychological & BehavioralGLP-1 and addiction pathways — looking for input Page 3

GLP-1 and addiction pathways — looking for input

DanielChem_CHI Sun, Apr 5, 2026 at 12:31 PM 12 replies 857 viewsPage 3 of 3
Dr.NephBHM_UK
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Jun 2024
Birmingham, UK
Apr 5, 2026 at 4:46 PM#11

nick_newbie — wow. I've been looking for this exact info for weeks.

5 11Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 2 others
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maria_elpaso
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Sep 2024
El Paso, TX
Apr 5, 2026 at 5:03 PM#12

Slightly tangential to GLP-1 and addiction but DanielChem_CHI reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

21 9RunnerRach, TrialNerd_Beth, HPLC_Greg and 18 others
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tommy_boulder
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Nov 2024
Boulder, CO
Apr 5, 2026 at 5:20 PM#13

Thanks for sharing this, DanielChem_CHI. A few questions about your GLP-1 and addiction experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about GLP-1 and addic?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

9 6robert_kc, dan_philly, MeganSA_TX and 6 others
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DanielChem_CHI
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Mar 2024
Chicago, IL
Apr 5, 2026 at 5:37 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on GLP-1 and addiction.

To answer maria_elpaso: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Apr 5, 2026 at 7:37 PM
30 24ben_calgary, patPC_UT, Dr.DermMIA and 27 others
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josh_phd_bmore
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Jul 2024
Baltimore, MD
Apr 5, 2026 at 5:54 PM#15

Relevant to GLP-1 and addiction pathways — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 207 → 107 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

23 16tampaLisa73, KarenAZ_mom, zoe_NC and 20 others
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