OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with de.
To answer PharmacoVig_BOS: yes, I am on compounded sema from a 503B pharmacy.
Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Relevant to Has anyone dealt with de novo — here is my latest bloodwork comparison:
Key improvements: A1C 8.4% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Slightly tangential to Has anyone dealt with de but WendyG_ATL reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
NurseLeah_Nash said:Thank you all for the thoughtful replies on Has anyone dealt with de
This is exactly right. NurseLeah_Nash articulated what I have been trying to explain to my doctor for months. The Has anyone dealt with de aspect is the most important factor.