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ForumsPharmacology & MechanismsWhy does it stop working after a while for some people — anyone have experience? Page 2

Why does it stop working after a while for some people — anyone have experience?

kim_atl_prep Thu, Sep 18, 2025 at 5:27 PM 38 replies 2,109 viewsPage 2 of 8
pat_auckland
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Sep 18, 2025 at 8:17 PM#6

Subscribing to this thread. Why does it stop working is exactly what I've been researching. 🙏

20 4NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 17 others
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kim_atl_prep
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Atlanta, GA
Sep 18, 2025 at 8:34 PM#7

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Why does it stop working.

To answer PharmD_Rodriguez: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

18 7BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 15 others
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dave_SLC
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Salt Lake City, UT
Sep 18, 2025 at 8:51 PM#8

Relevant to Why does it stop working after — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 227 → 97 mg/dL, hsCRP 6.0 → 0.9 mg/L. All on tirzepatide for 7 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

23 11james_edin, FranDenver, Dr.BariatricHTX and 20 others
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PeptideSynthNJ
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Princeton, NJ
Sep 18, 2025 at 9:08 PM#9
kim_atl_prep said:
Thank you all for the thoughtful replies on Why does it stop working

This is exactly right. kim_atl_prep articulated what I have been trying to explain to my doctor for months. The Why does it stop working aspect is the most important factor.

35 4MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 32 others
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amsterdam_pete
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Sep 18, 2025 at 9:25 PM#10

Slightly tangential to Why does it stop working but LarryQC_SD reminded me — has the insurance landscape changed recently?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Sep 19, 2025 at 3:25 AM
34 9ChrisMacros, KetoKyle, CanadaChris and 31 others
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